Dr. Purkayastha pioneered Neuro-endovascular Surgery in Kolkata in 2006 and is currently associated with Manipal Hospitals Mukundapur, where he leads a dedicated Neuro-interventional Unit. Equipped with the state-of-the-art Siemens ICONO Biplane Neuro Cathlab System, the centre delivers advanced minimally invasive treatments for stroke, brain aneurysms, arteriovenous malformations (AVMs), fistulae, and spinal vascular disorders. These innovative procedures help reduce the need for open brain surgery, enabling faster recovery and improved outcomes. The unit is also known for its strong academic focus, fellowship training, and research initiatives, attracting physicians from across India and Bangladesh for specialised training, knowledge exchange, and collaborative clinical excellence in this rapidly evolving field.